This is an issue that originates in Skype and which has been fixed in the new Skype 4.0 version.

Skype 4.0 contains a fix for audio de-sync bug during a call. In some situations the Skype audio would loose time sync and your voice would overlap with the other sides voice, obviously not the ideal effect.

Those that have the issue please upgrade to Skype 4.0. It also has the new "Compact Mode" which makes Skype 4.0 behave as Skype 3.8 did (visually). For those that resented the new, larger user interface you can now use compact mode and this works great!

Download 4.0 from Skype: http://www.skype.com/go/downloading-beta

No Pamela upgrade is required as the bug originates in Skype.